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Epidemiological And Molecular Aspects On Cholera (Infectious Disease)
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Epidemiological And Molecular Aspects On Cholera (Infectious Disease)

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Epidemiological And Molecular Aspects On Cholera (Infectious Disease)

S. K. Bhattacharya T. Ramamurthy

Published by Springer | Language - English | Binding - Hard Bound

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` 16500 (19% off) ` 13340

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Though cholera is an ancient disease, its perennial occurrence in several parts of the world has attracted many researches to find ways and means to combat the disease. The prevailing seventh pandemic cholera is dominating since 1961, but the dimension of the disease has taken several silhouettes, as the genetic structure and functions of the Vibrio cholerae has changed to a great extent. Several recent studies have shown that transformation of the pathogen at the molecular level has ameliorated several cholera outbreaks and epidemics of with successive new clones of V. cholerae.
This comprehensive compilation, written by eminent international researchers reviews the epidemiology of cholera in Africa, Asia, Russia and Latin Americas. The other chapters contributed by acclaimed authors cover various aspects on evolution, polysaccaharide biosynthesis, SXT element, integrons, small molecule signalling systems, flagellar synthesis, filamentous phages, pathogenic role of proteases and hemolysin, and other putative virulence factors. In addition, ecology of V. cholerae and management of cholera were also discussed in detail.
This book will be good source of information to all researchers with interests in infectious diseases, microbiology and molecular biology.

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Reviewer: Carlos E Figueroa Castro, MD(Boone Hospital Center)
Description: Part of a series on infectious diseases, this book covers current epidemiological and molecular aspects of cholera.
Purpose: The main purpose is to detail current developments in the field while avoiding redundancy. Given recent events in Haiti, this book will be of value for researchers wishing up-to-date information on cholera.
Audience: It is very obvious the book is most appropriate for researchers in cholera and other enteric diseases. Although not an impossible task, novice readers will find this book difficult to read. The authors are recognized authorities in cholera research.
Features: The majority of the chapters are detailed descriptions of the epidemiology and molecular biology of Vibrio cholerae infection. However, one chapter covers clinical management. It would be most helpful for readers unfamiliar with this subject to start with chapters 6 and 7. The book could have used more illustrations.
Assessment: The book requires a certain level of knowledge of cholera in order to be useful. Healthcare providers looking for basic information, especially involving clinical management, are better served by clinical textbooks in infectious diseases.

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Table Of Contents:

1 General Introduction T. Ramamurthy S.K. Bhattacharya 1

2 Asiatic Cholera: Mole Hills and Mountains Asish K. Mukhopadhyay T. Ramamurthy 5

3 Endemic and Epidemic Cholera in Africa Samba Sow Martin Antonio Joe O. Oundo Inacio Mandomando T. Ramamurthy 31

4 Phenotypic and Molecular Characteristics of Epidemic and Non-epidemic Vibrio cholerae Strains Isolated in Russia and Certain Countries of Commonwealth of Independent States (CIS) Elena V. Monakhova 51

5 The Re-emergence of Cholera in the Americas Gabriela Delgado Rosario Morales Jose Luis Mendez Alejandro Cravioto 79

6 The Evolution of Vibrio cholerae as a Pathogen John Joseph Mekalanos 97

7 Molecular Epidemiology of Toxigenic Vibrio cholerae Shah M. Faruque G. Balakrish Nair Yoshifumi Takeda 115

8 Diversity and Genetic Basis of Polysaccharide Biosynthesis in Vibrio cholerae Shanmuga Sozhamannan Fitnat H. Yildiz 129

9 Significance of the SXT/R391 Family of Integrating Conjugative Elements in Vibrio cholerae Vincent Burras 161

10 Small Molecule Signaling Systems in Vibrio cholerae Rupak K. Bhadra Sangita Shah Bhabatosh Das 185

11 Vibrio cholerae Flagellar Synthesis and Virulence Khalid Ali Syed Karl E. Klose 203

12 Filamentous Phages of Vibrio cholerae 01 and 0139 Masahiko Ehara M. John Albert 213

13 Pathogenic Potential of Non-01, Non-0139 Vibrio cholerae Amit Sarkar Ranjan K. Nandy Asoke C. Ghose 223

14 Proteases Produced by Vibrio cholerae and Other Pathogenic Vibrios: Pathogenic Roles and Expression Sumio Shinoda 245

15 Toxins of Vibrio cholerae and Their Role in Inflammation, Pathogenesis, and Immunomodulation Kamini Walia Nirmal Kumar Ganguly 259

16 Vibrio cholerae Hemolysin: An Enigmatic Pore-Forming Toxin Kalyan K. Banerjee Budhaditya Mazumdar 277

17 Integron-Mediated Antimicrobial Resistance in Vibrio cholerae Amit Ghosh T. Ramamurthy 291

18 Aquatic Realm and Cholera Anwar Huq Chris J. Grim Rita R. Colwell 311

19 Management of Cholera P. Dutta D. Sur S. K. Bhattacharya 341

Subject Index 355


Book: Epidemiological And Molecular Aspects On Cholera (Infectious Disease)
Author: , ,
ISBN-13: 9781603272643
Product Code 9781603272643
Binding: Hard Bound
Publishing Date: 2010-10-01
Publisher: Springer
Number of Pages: 310
Language: English

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